RLE Computational Biophysics Group is focused on understanding conformational
changes in biomolecules that play an important role in common human
diseases. The group uses an interdisciplinary approach combining
computational modeling with biochemical experiments to make connections
between conformational changes in macromolecules and disease progression.
By employing two types of modeling, molecular dynamics and probabilistic
modeling, hypotheses can be developed and then tested experimentally.
Doing double duty: MIT's Collin Stultz