The RLE Computational Biophysics Group is focused on understanding conformational changes in biomolecules that play an important role in common human diseases. The group uses an interdisciplinary approach combining computational modeling with biochemical experiments to make connections between conformational changes in macromolecules and disease progression. By employing two types of modeling, molecular dynamics and probabilistic modeling, hypotheses can be developed and then tested experimentally.  

See a video introduction to our group