Selected Papers:

Salsas-Esat R., Stultz CM., Conformational Selection and Collagenolysis in Type III Collagen. Proteins: Structure, Function, and Bioinformatics (DOI 10.1002/prot.2254), 2009

Phillips C., Nerenberg P., Drennan C., Stultz CM. The Physical Basis of Metal Binding Specificity in E. coli NikR. Journal of the American Chemical Society 131(29), 10220-10228 (DOI: 10.1021/ja9026314), 2009

Syed Z., Stultz CM., Kellis M., Indyk P. Guttag J. Motif Discovery in Physiological Datasets: A Methodology for Inferring Predictive Elements. ACM Transactions on Knowledge Discovery from Data. (In press).

Schubert C., Stultz CM. The Multi-Copy Simultaneous Search Methodology: A Fundamental Tool for Structure-Based Drug Design. Journal of Computer Aided Molecular Design (DOI 10.1007/s10822-009-9287-y), 2009.

Huang A., Stultz CM. Finding Order within Disorder: Elucidating the Structure of Proteins Associated with Neurodegenerative Disease. Future Medicinal Chemistry 1(3):467-482, 2009.

Syed Z., Sung P., Sciric BM., Morrow, DA.  Stultz CM., Guttag JV. Spectral Energy of ECG Morphologic Differences to Predict Death.  Cardiovascular Engineering (DOI 10.1007/s10558-009-9066-3), 2009.

Yoon M., Venkatachalam V., Huang A., Choi B., Stultz CM., Chou JJ. Residual structure within the disordered C-terminal segment of p21Waf1/Cip1/Sdi1 and its implications for molecular recognition. Protein Science 18(2):337-347, 2009.

Syed S.., Scirica BM., Mohanavelu S., Sung P., Cannon CP., Stone PH., Stultz CM., Guttag JG. Relation of Death Within 90 Days of Non-ST-Elevation Acute Coronary Syndromes to Variability in Electrocardiographic Morphology. American Journal of Cardiology, 103(3):307-311 (DOI: 10.1016/j.amjcard.2008.09.099), 2009.

Huang A., Stultz CM. The Effect of a ΔK280 Mutation on the Unfolded State of a Microtubule Binding Repeat in Tau. PLoS Computational Biology4(8): e1000155 doi:10.1371/journal.pcbi.1000155 .

Nerenberg P., Stultz CM. Differential Unfolding of α1 and α2 chains in Type I Collagen and Collagenolysis. JMB 382, 246-256, 2008.

Gee PS. Gee, Ingber DE., Stultz CM. Fibronectin Unfolding Revisited: Modeling Cell Traction-mediated Unfolding of the Tenth Type-III Repeat Running Title: Fibronectin Unfolding Revisited.  PLoS ONE, 3(6): e2373. doi:10.1371/journal.pone.0002373.

Nerenberg P., Salsas-Escat R., Stultz CM. Do collagenases unwind triple-helical collagen prior to peptide bond hydrolysis? Reinterpreting experimental observations with mathematical models. Proteins: Structure, Function, and Bioinformatics, 70: 1154-1161, 2008.

Nerenberg P., Salsas-Escat R., Stultz CM. Collagen – A Necessary Accomplice in the Metastatic Process. Cancer Genomics & Proteomics 4: 319-328 (2007).

Salsas-Escat R., Stultz CM. The Molecular Mechanics of Collagen Degradation:  Implications for Human Disease. Experimental Mechanics (Published online ahead of print DOI10.1007/s11340-007-9105-1).

Syed Z., Guttag J., and Stultz CM. Clustering and Symbolic Analysis of Cardiovascular Signals: Discovery and Visualization of Medically Relevant Patterns in Long-Term Data Using Limited Prior Knowledge. 2007; EURASIP Journal on Advances in Signal Processing, vol. 2007, Article ID 67938, 16 pages.

Thomas A., Edelman ER., Stultz CM. Collagen Fragments Modulate Innate Immunity. 2007; Exp. Biol. & Med. 232: 406-411

Huang, A. & Stultz CM. Conformational Sampling with Implicit Solvent Models: Application to the PHF6 Peptide in Tau Protein. 2007; Biophys. J.  92: 34–45.

Stultz, CM. The Folding Mechanism of Collagen-like Model Peptides Explored through Detailed Simulations. Protein Science. 2006; 15: 2166-2177.

Stultz CM. Cosmology and proteins: landscape of possibilities.  Nature Physics. 2006; 2(6): 357.

Stultz CM., Karplus M. In Fragment-based Approaches in Drug Discovery. Methods and Principles in Medicinal Chemistry v34. eds. Jahnke and Erlanson, Wiley-VCH, Weinheim. 2006. pg. 125-148.

Stultz CM. An Assessment of Potential of Mean Force Calculations with Implicit Solvent Models. J. Chem. Phys B. 2004; 108:16525-16532. 

Stultz CM, Edelman ER. A Structural Model that Explains the Effects of Hyperglycemia on Collagenolysis. Biophys. J. 2003; 85:2198-2204. 

Stultz CM. Localized Unfolding of Collagen Explains Collagenase Cleavage Near Imino-Poor Sites. J. Mol. Biol. 2002;319:997-1003. 

Stultz CM, Levin AD, Edelman ER. Phosphorylation Induced Conformational Changes in a MAP-Kinase Substrate: Implications for Tyrosine Hydroxylase Activation. J. Biol. Chem. 2002;277:47653-47661.

Stultz CM, Karplus M. Dynamic Ligand Design and Combinatorial Optimization. Proteins, Structure Function and Genetics. 2000; 40: 259-289. 

Stultz CM, Karplus M. MCSS Functionality Maps for a Flexible Protein. Proteins, Structure Function and Genetics. 1999;37:512-529. 

Stultz CM, Karplus M. On the Potential Surface of the Locally Enhanced Sampling Approximation. Journal of Chemical Physics. 1998; 109: 8809-8815. 

Stultz CM, Nambudripad R, Lathrop R, White JV. Predicting Protein Structure with Probabilistic Models. In: Protein Structural Biology in Bio-Medical Research , Vol. 22B of Advances in Molecular and Cell Biology series editor: E. E. Bittar, Guest Editors: N.M. Allewell and C. Woodward.  Greenwich CT: JAI Press ;1997. p. 447-506.

White JV, Stultz CM, Smith TF. Protein Classification by Stochastic Modeling and Optimal Filtering of Amino-Acid Sequences. Mathematical Biosciences. 1994; 119: 35-75. 

Stultz CM, White JV, Smith TF. Structural Analysis Based on State Space Modeling. Protein Science. 1993; 2: 305-314.