Micro / Nanofluidic BioMEMS Group, Professor Jongyoon Han
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Publications
 

Papers in Refereed journals

2008

  1. Song, Y.-A., Batista, C., Sarpeshkar, R., Han, J., "Rapid fabrication of microfluidic polymer electrolyte membrane fuel cell in PDMS by surface patterning of perfluorinated ion-exchange resin", Journal of Power Sources 2008 (doi)
  2. Sung Jae Kim, Jongyoon Han, "Self-Sealed Vertical Polymeric Nanoporous-Junctions for
    High-Throughput Nanofluidic Applications," Anal. Chem. 2008, 80, 3507-3511. (doi)
  3. Zi Rui Li, Z.R., Gui Rong Liu, Yu Zong Chen, Jian-Sheng Wang, Hansen Bow, Yuan Cheng, Jongyoon Han, “Continuum Transport Model of Ogston Sieving in Patterned Nanofilter Arrays for Rod-like Biomolecule Separation, ” Electrophoresis, accepted for publication 2008.
  4. Lee, J. H.; Song, Y.-A; Tannenbaum, S., Han, J. Increase of Reaction Rate and Sensitivity of Low-Abundance Enzyme Assay using Micro/Nanofluidic Preconcentration Chip," Anal. Chem., accepted for publication, 2008
  5. Chung S., Lee J. H., Moon M-W., Han J, Kamm R. D. "Non-lithographic wrinkle nanochannels for protein preconcentration," Adv. Mater., accepted for publication, 2008.
  6. Lee J. H*.; Song Y.-A.*; Han J. "Multiplexed Proteomic Sample Preconcentration Device Using Surface-Patterned Ion-Selective Membrane," Lab Chip 2008, (doi). * These authors contributed equally to this work.
  7. Han J., Fu J., and Schoch R.B., “Molecular Sieving Using Nanofilters: Past, Present and Future,” Lab on a Chip, 2008, (doi)
  8. Wang YC, and Han J, "Pre-binding dynamic range and sensitivity enhancement for immuno-sensors using nanofluidic preconcentrator," Lab on a Chip, 2008, (doi)

 

2007

  1. Schoch, R.B., Cheow, L.F., and Han, J., “Electrical Detection of Fast Reaction Kinetics in Nanochannels with an Induced Flow,” Nano Letters, ASAP Web Release Date: 2007-11-13; (Letter) (doi) (reprint)
  2. Lee, J. H., Chung, S., Kim, S. J. & Han, J. "Novel PDMS based protein preconcentration using a nanogap generated by junction gap breakdown,” Analytical Chemistry, 79, 6868 -6873, 2007. accepted. (doi)
  3. Schoch, R.B., Han, J., and P. Renaud P., Transport phenomena in nanofluidics. Reviews of Modern Physics, 2007. to appear.
  4. Kim, S. J.*, Wang, Y.-C.*, Lee, J. H., Jang, H. & Han, J. "Concentration polarization and nonlinear electrokinetic flow near a nanofluidic channel,” Physical Review Letters, 99, 044501.1-4 (2007). (pdf‡)
  5. Duong-Hong, D., Wang, J.-S., Liu, G. R., Chen, Y. Z., Han, J., Hadjiconstantinou, N. G. " Dissipative particle dynamics simulations of electroosmotic flow in nano-fluidic devices," Microfluidics and Nanofluidics 3 (2007). (doi)
  6. Fu, J.*, Schoch, R. B.*, Stevens, A. L., Tannenbaum, S. R. & Han, J. "A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and proteins,” Nature Nanotechnology 2, 121-128 (2007). (pdf) Comment: Austin, R. "Nanofluidics: a fork in the nano-road," Nature Nanotechnology 2, 79-80 (2007). (pdf)

2006

  1. Kim, S. J., Song, Y.-A., Skipper, P. L. & Han, J. "Electrohydrodynamic generation and delivery of monodisperse pico-liter droplets using the PDMS microchip," Analytical Chemistry 78, 8011-8019 (2006). (doi)
  2. Balducci, A., Mao, P., Han, J. & Doyle, P. S."Double-stranded DNA diffusion in slitlike nanochannels," Macromolecules 39, 6273-6281 (2006). (doi)
  3. Fu, J., Yoo, J. & Han, J. "Molecular sieving in periodic free-energy landscapes created by patterned nanofilter arrays," Physical Review Letters 97, 018103.1-4 (2006). (pdf‡)
  4. Song, Y.-A., Hsu, S., Stevens, A. & Han, J. "Continuous-flow pI-based sorting of proteins and peptides in a microfluidic chip using diffusion potential," Analytical Chemistry 78, 3528-3536 (2006). (doi)

2005

  1. Fu, J., Mao, P. & Han, J. "A nanofilter array chip for fast gel-free biomolecule separation," Applied Physics Letters 87, 263902.1-3 (2005). (pdf†)
  2. Mao, P. & Han, J. "Fabrication and characterization of 20 nm nanofluidic channels by glass-glass and glass-silicon bonding," Lab on a Chip 5, 837-844 (2005). (pdf§)
  3. Wang, Y.-C., Stevens, A. & Han, J. "Million-fold preconcentration of proteins and peptides by nanofluidic filter," Analytical Chemistry 77, 4293-4299 (2005). (doi)

2004

  1. Han, J. & Singh, A. K. "Rapid protein separations in ultra-short microchannels: microchip sodium dodecyl sulfate-polyacrylamide gel electrophoresis and isoelectric focusing," Journal of Chromatrography A 1049, 205-209 (2004). (pdf, doi)
  2. Wang, Y.-C., Choi, M. H. & Han, J. "Two-dimensional protein separation with advanced sample and buffer isolation using microfluidic valves," Analytical Chemistry 76, 4426-4431 (2004). (doi)

Previous to 2002 (non-MIT)

  1. Han, J. & Craighead, H. G. "Characterization and optimization of an entropic trap for DNA separation," Analytical Chemistry 74, 394-401 (2002).
  2. Han, J. & Craighead, H. G. "Separation of long DNA molecules in a microfabricated entropic trap array," Science 288, 1026-1029 (2000).
  3. Chou, C.-F., Austin, R. H., Bakajin, O., Tegenfeldt, J. O., Castelino, J. A., Chan, S. S., Cox, E. C., Craighead, H. G., Darnton, N., Duke, T., Han, J. & Turner S. "Sorting biomolecules with microdevices," Electrophoresis 21, 81-90 (2000).
  4. Han, J., Turner, S. W. & Craighead, H. G. "Entropic trapping and escape of long DNA molecules at submicron size constriction," Physical Review Letters 83, 1688-1691 (1999).
  5. Han, J. & Craighead, H. G. "Entropic trapping and sieving of long DNA molecules in a nanofluidic channel," Journal of Vacuum Science Technology A 17, 2142-2147 (1999).
  6. Hill, S. B., Haich, C. A., Dunning, F. B., Walters, G. K., McClelland, J. J., Celotta, R. J., Craighead, H. G., Han, J. & Tanenbaum, D. M. "Patterning of octadecylsiloxane self-assembled monolayers on Si(100) using Ar(P-3(0,2)) atoms," Journal of Vacuum Science Technology B 17, 1087-1089 (1999).
  7. Han, J., Kuk, Y. & Jeon, D. "Surface crystalline gold silicide formation on the Au(100) surface," Surface Science 376, 237-244 (1997).

 

Proceedings of refereed conFerences

2006

  1. Fu, J. & Han, J. "Continuous-flow biomolecule separation through patterned anisotropic nanofluidic sieving structure," Proceedings of the MicroTAS 2006 Symposium, Tokyo, Japan, vol. 1, pp. 519-521. (oral presentation)
  2. Kim, S. J., Wang, Y.-C., Jang, H., Lee, J. H. & Han, J. "Nonlinear electrokinetic flow pattern near nanofluidic channel," Proceedings of the MicroTAS 2006 Symposium, Tokyo, Japan, vol. 1, pp. 522-524. (oral presentation)
  3. Kim, S. J., Song, Y. A., Skipper, P. L., Tannenbaum, S. R. & Han, J. "Generation and delivery of monodisperse pico-liter droplets out of PDMS microchip into accelerator mass spectrometry (AMS)," Proceedings of the MicroTAS 2006 Symposium, Tokyo, Japan, vol. 2, pp. 1076-1078. (poster presentation)

2005

  1. Mao, P. & Han, J. "Fabrication and characterization of planar nanofluidic channels and massively-parallel nanofluidic membranes," Proceedings of the MicroTAS 2005 Symposium, Boston, MA, vol. 1, pp. 678-680. (poster presentation)
  2. Wang, Y.-C., Tsau, C. H., Burg, T. P., Manalis, S. & Han, J. "Efficient biomolecule pre-concentration by nanofilter triggered electrokinetic trapping," Proceedings of the MicroTAS 2005 Symposium, Boston, MA, vol. 1, pp. 238-240. (poster presentation)
  3. Fu, J. & Han, J. "A nanofilter array chip for fast gel-free biomolecule separation," Proceedings of the MicroTAS 2005 Symposium, Boston, MA, vol. 2, pp. 1531-1533. (oral presentation)
  4. Song, Y.-A. & Han, J. "Continuous pI-based sorting of proteins and peptides in an microfluidic chip using diffusion potential," Proceedings of the MicroTAS 2005 Symposium, Boston, MA, vol. 2, pp. 1025-1027. (oral presentation)
  5. Wang, Y.-C., Fu, J., Mao, P. & Han, J. "Nanofluidic molecular filters for efficient protein separation and preconcentration", Proceedings of the Transducers 2005 conference, Seoul, Korea, vol. 1, pp. 352-355. (oral presentation)

2004

  1. Fu, J. & Han, J. "Biomolecule separation in nanofluidic filters by steric hindrance mechanism," Proceedings of the MicroTAS 2004 Symposium, Malmo, Sweden, vol. 1, pp. 285-287. (poster presentation)
  2. Han, J. & Fu J. "Biomolecule separation by steric hindrance using nanofluidic filters," 2004 IEEE-EMBS meeting, San Francisco, CA, pp. 2611-2614. (invited presentation)
  3. Choi, M. H., Wang, Y. -C. & Han, J. "On-chip isoelectric focusing coupled to micro liquid chromatography in blood proteomics," Proceedings of the MicroTAS 2004 Symposium, Malmo, Sweden, vol. 2, pp. 255-257. (poster presentation)

2003

  1. Wang, Y.-C., Choi, M. H. & Han, J. "On-chip IEF peak manipulation for 2D protein separation and MS coupling," Proceedings of the MicroTAS 2003 Symposium, Squaw Valley, CA, pp. 955-958. (poster presentation)

Previous to 2002 (non-MIT)

  1. Han, J. & Singh, A. K. "Miniaturization of protein separation: isoelectric focusing and SDS-PAGE," Proceedings of the MicroTAS 2002 Symposium, Nara, Japan, vol. 1, pp. 596-598. (poster presentation)
  2. Han, J. & Craighead, H. G. "From microfluidics to nanofluidics: DNA separation using nanofluidic entropic trap array device," Proceedings of SPIE 2000 - The International Society for Optical Engineering, 4177, pp. 42-48. (invited talk)


Other major publications

  1. Han, J. "Nanofluidics," a textbook chapter in "Introduction to Nanoscale Science and Technology," eds. Di Ventra, M., Evoy, S. & Heflin, J. R. (Kluwer Academic Publishers, Boston, 2004).

 

* These authors contributed equally to this work.

† Copyright by American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

‡ Copyright by the American Physical Society.

§ Do not make further available or distribute.

  
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