Micro / Nanofluidic BioMEMS Group, Professor Jongyoon Han
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Research
 

Just as information in electrical circuits is represented by the movement of electrons and holes, information in biological systems is transmitted, amplified, and processed by the actions of proteins on various biomolecules. These biomolecules include DNA, RNA, proteins, and ions. Understanding biological information processing is important, but we currently lack good tools for measuring these biological signals.

Our group focuses on developing tools for detecting, identifying, quantifying, and sorting biomolecules. These tools for biology are analogous to the oscilloscope for electrical engineering. To develop these tools, we use micro/nanofabrication methods that are commonly used to develop MEMS (Micro Electro Mechanical Systems). The size scales that can be achieved using these methods enable access to phenomena relevant to biological systems.

PROJECTS

Hindered Diffusion of Biomolecules Confined in a Nanofluidic Channel
Hindered Diffusion of Biomolecules Confined in a Nanofluidic Channel
Fabrication and Characterization of Nanofluidic Channels for Studying Molecular Dynamics in Confined Environments
Fabrication and Characterization of Nanofluidic Channels for Studying Molecular Dynamics in Confined Environments
Multi-Dimensional Protein/Peptide Separation
Multi-Dimensional Protein/Peptide Separation
     
Biomolecule Preconcentration using Nanofluidic Filters
Biomolecule Preconcentration using Nanofluidic Filters
Protein and DNA Separation with Patterned Periodic Nanofluidic Filters
Microfabricated Nanofluidic Sieving Structures for Rapid Biomolecule Separation

Sorting by diffusion potential

Continuous-Flow pI-Based Sorting of Proteins and Peptides in a Microfluidic Chip using Diffusion Potential

     
Electrohydrodynamic Microdroplet Generation
Electrohydrodynamic Microdroplet Generation
Self-Sealed Vertical Polymeric Nanoporous-Junctions for High-Throughput Nanofluidic Applications
 
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