Publication Record
Asterisks* indicate co-first-authorship, underlines indicate corresponding authorship

Peer-Reviewed Articles

A. Cheng and T. K. Lu, "Synthetic Biology: An Emerging Engineering Discipline," Annual Review of Biomedical Engineering, May 7, 2012 [epub ahead of print]. [pdf]

(http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-071811-150118)

A. F. Radovic-Moreno, T. K. Lu, V. A. Puscasu, C. J. Yoon, R. Langer, and O. C. Farokhzad, "Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics," ACS Nano, April 3, 2012 [epub ahead of print]. [pdf]

(http://pubs.acs.org/doi/abs/10.1021/nn3008383)

K. E. Kaseniit, S. Perli, T. K. Lu, “Designing Extensible Protein-DNA Interactions for Synthetic Biology,” Proceedings of the 2011 IEEE Biomedical Circuits and Systems Conference (BioCAS), pp. 349-352, November 10-12, 2011. [pdf]

T. K. Lu and M. Koeris, “The Next Generation of Bacteriophage Therapy,” Current Opinion in Microbiology, vol. 14, no. 5, pp. 524-531, October, 2011. [pdf]

(http://www.sciencedirect.com/science/article/pii/S1369527411001123)

T. K. Lu, “Engineering Scalable Biological Systems,” Bioengineered Bugs, vol. 1, no. 6, pp. 1-6, November/December, 2010. [pdf]

(http://www.landesbioscience.com/journals/31/article/13086/)

T. K. Lu, A. S. Khalil, and J. J. Collins, “Next-Generation Synthetic Gene Networks,” Nature Biotechnology, vol. 27, no. 12, pp. 1139-1150, December 7, 2009. [pdf]
(http://www.nature.com/nbt/journal/v27/n12/abs/nbt.1591.html )

A. E. Friedland*, T. K. Lu*, X. Wang, D. Shi, G. M. Church, and J. J. Collins, “Synthetic Gene Networks that Count,” Science, vol. 324, no. 5931, pp. 1199-1202, May 29, 2009. [pdf]
(http://www.sciencemag.org/cgi/content/abstract/324/5931/1199 )

T. K. Lu and J. J. Collins, “Engineering Synthetic Bacteriophage to Combat Antibiotic-Resistant Bacteria,” Proceedings of the 35th Annual Northeast Bioengineering Conference, April 3-5, 2009.

T. K. Lu and J. J. Collins, “Engineered Bacteriophage Targeting Gene Networks as Adjuvants for Antibiotic Therapy,” Proceedings of the National Academy of Sciences, vol. 106, no. 12, pp. 4629-4634, March 24, 2009. [pdf]
(http://www.pnas.org/content/106/12/4629.abstract )

T. K. Lu and J. J. Collins, “Dispersing Biofilms with Engineered Enzymatic Bacteriophage,” Proceedings of the National Academy of Sciences, vol. 104, no. 27, pp. 11197-11202, July 3, 2007.  [pdf]
(http://www.pnas.org/cgi/content/abstract/0704624104v1).  In the top 15 most read articles in July 2007.

T. K. Lu, S. Zhak, P. Dallos, and R. Sarpeshkar, “Fast cochlear amplification with slow outer hair cells,” Hearing Research, vol. 214, no. 1-2, pp. 45-67, April 2006. [pdf] (http://dx.doi.org/10.1016/j.heares.2006.01.018)

T. K. Lu, S. Zhak, P. Dallos, and R. Sarpeshkar, “A Micromechanical Model for Fast Cochlear Amplification with Slow Outer Hair Cells,” Proceedings of the International Symposium on Auditory Mechanisms:  Processes and Models, Portland, OR, pp. 433-441, July 23-28, 2005.

R. Sarpeshkar, C. Salthouse, J.-J. Sit, M. Baker, S. Zhak, T. K.-T. Lu, L. Turicchia, and S. Balster, “An Ultra-Low-Power Programmable Analog Bionic Ear Processor,” IEEE Transactions on Biomedical Engineering, vol. 52, no. 4, pp. 711-727, April 2005. [pdf]
(http://dx.doi.org/10.1109/TBME.2005.844043)

M.W. Baker, T. K.-T. Lu, and R. Sarpeshkar, “A Low-Power AGC with Level Independent Phase Margin,” IEEE 2004 American Controls Conference, Boston, MA, vol. 1, pp. 386-389, June 30 – July 2, 2004.

M.W. Baker, T. K.-T. Lu, C.D. Salthouse, J.-J. Sit, S. Zhak, and R. Sarpeshkar, “A 16-channel Analog VLSI Processor for Bionic Ears and Speech-Recognition Front Ends,” Proceedings of the IEEE Custom Integrated Circuits Conference, San Jose, CA, vol. 23, no. 4, pp. 521-526, September 21-24, 2003. 
(http://dx.doi.org/10.1109/CICC.2003.1249452)

T. K.-T. Lu, M. Baker, C. Salthouse, J.-J. Sit, S. Zhak, and R. Sarpeshkar, “A Micropower Analog VLSI Processing Channel for Bionic Ears and Speech-Recognition Front Ends,” Proceedings of the 2003 IEEE International Symposium on Circuits and Systems (ISCAS 2003), Bangkok, Thailand, vol. 5, pp. 41-44, May 25-28, 2003. 
(http://dx.doi.org/10.1109/ISCAS.2003.1206169)

Technical Reports

T. K. Lu, S. Zhak, P. Dallos, and R. Sarpeshkar, “Fast Cochlear Amplification with Slow Outer Hair Cells,” Massachusetts Institute of Technology Microsystems Technology Laboratories Annual Research Report, p. 40, September 2006.

SELECTED PRESENTATIONS

“Scalable and Tunable Platforms for Engineering Synthetic Gene Circuits,” 2011 MIT Research and Development Conference, Cambridge, MA, November 15, 2011.

“Synthetic Gene Circuits for Scalable Biological Design,” Fifth Annual Workshop on the Business-Government Interface, Forum on Systems and Synthetic Biology, Braga, Portugal, June 6, 2011.

“Synthetic Biology: Engineering and Reengineering Life,” 10 Conference, Leavenworth, WA, May 20, 2011.

“Debugging Superbugs with Engineered Phages,” The Mathematics of Microbes: Biophysical Details of the
Evolving Cell, London, United Kingdom, April 29, 2011.

“Debugging Biofilms and Superbugs,” Invited Talk, Institute of Medicine Board on Global Health, Forum on
Microbial Threats, Washington, DC , March 15, 2011.

“Next-Generation Antimicrobial Agents for Combating Antibiotic-Resistant Bacteria,” 27th Army Science
Conference, Orlando, FL, November 30, 2010.

“Synthetic Biological Memory and Counter Circuits,” Kavli Frontiers of Science, Irvine, CA, November 13, 2009.

“Engineered Bacteriophage to Combat Bacterial Biofilms and Antibiotic-Resistant Bacteria,” Invited Talk, Covidien, New Haven, CT, May 28, 2009.

“Engineered Gene Circuits for Medicine,” Invited Talk, National Chiao-Tung University, Hsinchu, Taiwan, April 10, 2009.

“Engineered Gene Circuits for Medicine,” Special Seminar, Massachusetts Institute of Technology, Cambridge, MA, March 30, 2009.

“Engineered Bacteriophage to Combat Bacterial Biofilms and Antibiotic-Resistant Bacteria,” Invited Talk, Frontiers in Synthetic Biology: Engineering Genes, Genomes & Cells for Drug Discovery, Boston, MA, December 1-2, 2008.

“Dispersing Biofilms with Engineered Enzymatic Bacteriophage,” Harvard-MIT Health Sciences and Technology Forum, Cambridge, MA, March 8, 2007.

“Engineered Phage for Enhanced Biofilm Removal,” Harvard-MIT Health Sciences and Technology Forum, Cambridge, MA, March 23, 2006.

PEER-REVIEWED ABSTRACTS

R. Krishnan, T. K. Lu, K. L. Allendoerfer, J. J. Collins, and S. Lindquist, “Molecular insights into the assembly of a bacterial amyloid,” American Chemical Society National Meeting and Exposition, August 16-20, 2009.

E. Perez, T. K. Lu, J. J. Collins, and R. M. Donlan, “Control of Escherichia coli Biofilm Formation on Urinary Catheters Using a Genetically Engineered Bacteriophage,” American Society for Microbiology General Meeting, May 20, 2009.